Oxidative stress is the medical equivalent of the sword of Damocles. On the one hand, its free radicals are essential for normal metabolism. On the other hand, it has been implicated in such a catastrophic and degenerative diseases such as stroke, myocardial infarction, chronic heart failure, diabetes, circulatory shock, chronic inflammatory diseases, cancer, asthma, atherosclerosis, cardiovascular disease, diabetes, Alzheimer's disease and neurodegenerative disorders. Oxidative stress is generally defined as an imbalance between oxidants and antioxidants. Evidence suggests that oxidative stress can lead to cell and tissue injury. All diseases involve free radikal high-wire balancing act between oxidants and antioxidants must be maintained to ensure the health of the aging process.
Research
great progress has been made recently in research and forensic analysis of oxidative stress. Of particular importance is the discovery of peroxynitrite the fastest non-enzymatic reactions in all of biology. His (NO) free radicals generated by the properties of nitric oxide, a critical engagement in a number of pathologies, such as vasodilation, neural signaling, and inflammation. (NO) is present and acts as a signaling device in every critical cellular function and crucial pathogenic mechanism of overwhelming oxidative injury such as cellular necrosis. However encouraging these recent discoveries is still much to be learned about the effects of peroxynitrite and oxidant properties to the cells on the repair process or to die.
There is general consensus that the reduction in oxidative stress may have some positive health benefits. Overproducing radical free radicals can overwhelm the immune system startup oxidative injury and illness some of which are already mentioned in micronutrients that play a role in the modulation of redox cell signaling provides an important foundation of the relationship between diet and health.
Conclusion Oxidative stress is a key factor in health and disease. Understanding of their bio-mechanics would go a long way in eradicating some of the most devastating pathologies of modern society.
